MMP2 抗体
(9 references)Quick Overview for MMP2 抗体 (ABIN2855854)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, Pig, 大鼠
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产品特性
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Rabbit Polyclonal antibody to MMP2 (matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase))
MMP2 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MMP2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 40-280) antibodyMMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 401-500) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B11E6 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibodyMMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 561-660) antibodyMMP2 适用: 人, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.4 mg/mL
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缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Chrysin Inhibits High Glucose-Induced Migration on Chorioretinal Endothelial Cells via VEGF and VEGFR Down-Regulation." in: International journal of molecular sciences, Vol. 21, Issue 15, (2020) (PubMed).
: "Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma." in: Oncology letters, Vol. 20, Issue 2, pp. 1685-1694, (2020) (PubMed).
: "Opsin 3 is a key regulator of ultraviolet A-induced photoageing in human dermal fibroblast cells." in: The British journal of dermatology, Vol. 182, Issue 5, pp. 1228-1244, (2020) (PubMed).
: "Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population." in: Cells, Vol. 9, Issue 8, (2020) (PubMed).
: "Nonspecific immunoglobulin G is effective in preventing and treating cancer in mice." in: Cancer management and research, Vol. 11, pp. 2073-2085, (2019) (PubMed).
: "miR‑338‑3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and β‑catenin signaling pathways." in: Molecular medicine reports, Vol. 20, Issue 1, pp. 33-40, (2019) (PubMed).
: "The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity." in: Scientific reports, Vol. 8, Issue 1, pp. 12995, (2019) (PubMed).
: "A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells." in: Oncotarget, Vol. 7, Issue 8, pp. 9429-47, (2017) (PubMed).
: "The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1." in: Scientific reports, Vol. 6, pp. 19874, (2016) (PubMed).
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: "Chrysin Inhibits High Glucose-Induced Migration on Chorioretinal Endothelial Cells via VEGF and VEGFR Down-Regulation." in: International journal of molecular sciences, Vol. 21, Issue 15, (2020) (PubMed).
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- matrix metallopeptidase 2
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背景
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Secreted , extracellular space , extracellular matrix -
分子量
- 74 kDa
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基因ID
- 4313
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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