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PYGB 抗体 (C-Term)

This anti-PYGB antibody is a 兔 多克隆 antibody detecting PYGB in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2855804
发货至: 中国

Quick Overview for PYGB 抗体 (C-Term) (ABIN2855804)

抗原

See all PYGB (GPBB) 抗体
PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

适用

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人, 小鼠

宿主

  • 65
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克隆类型

  • 65
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多克隆

标记

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This PYGB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    产品特性

    Rabbit Polyclonal antibody to GPBB (phosphorylase, glycogen, brain)
    GPBB antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human GPBB. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: HepG2 , mouse brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.84 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Cooper, Pasini, Lambert, DAlessandro, Yao, Risner, Calkins: "Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18810-18821, (2020) (PubMed).

    Geiszler, Ugun-Klusek, Lawler, Pardon, Yuchun, Bai, Daykin, Auer, Bedford: "Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons." in: Scientific reports, Vol. 8, Issue 1, pp. 4833, (2019) (PubMed).

  • 抗原

    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

    别名

    GPBB

    背景

    The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.

    分子量

    97 kDa

    基因ID

    5834

    途径

    Cellular Glucan Metabolic Process
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