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HPD 抗体

This anti-HPD antibody is a 兔 多克隆 antibody detecting HPD in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855744
发货至: 中国

Quick Overview for HPD 抗体 (ABIN2855744)

抗原

See all HPD 抗体
HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

适用

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宿主

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克隆类型

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多克隆

标记

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This HPD antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

KO Validated
  • 交叉反应

    产品特性

    Rabbit polyclonal antibody to HPD (4-hydroxyphenylpyruvate dioxygenase)
    HPD antibody [N1C2]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human HPD. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Shan, Lu, Li, Sheng, Fan, Qi, Liu, Zhang: "4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis." in: Cell death & disease, Vol. 10, Issue 7, pp. 525, (2020) (PubMed).

  • 抗原

    HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

    别名

    4-hydroxyphenylpyruvate dioxygenase

    背景

    The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    45 kDa

    基因ID

    3242

    UniProt

    P32754
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