HSD17B4 抗体
(1 reference)Quick Overview for HSD17B4 抗体 (ABIN2855717)
抗原
See all HSD17B4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to HSD17B4 (hydroxysteroid (17-beta) dehydrogenase 4)
HSD17B4 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human HSD17B4. The exact sequence is proprietary.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (N-Term) antibody
HSD17B4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (C-Term) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 437-736) antibodyHSD17B4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 510-736) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 744-761), (C-Term) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (N-Term) antibodyHSD17B4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 341-370) antibodyHSD17B4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31274 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 340-370), (Middle Region) antibodyHSD17B4 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Rat heart
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).
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: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).
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- HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
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别名
- hydroxysteroid 17-beta dehydrogenase 4
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背景
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The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.
Cellular Localization: Peroxisome -
分子量
- 80 kDa
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基因ID
- 3295
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UniProt
- P51659
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途径
- Monocarboxylic Acid Catabolic Process
抗原
-
