FGFRL1 抗体
Quick Overview for FGFRL1 抗体 (ABIN2855700)
抗原
See all FGFRL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
产品特性
-
Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
FGFR-5 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human FGFR5. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (AA 168-378) antibody
FGFRL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (AA 164-368) antibodyFGFRL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (AA 403-470) antibodyFGFRL1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) antibodyFGFRL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (Internal Region) antibodyFGFRL1 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (AA 164-374) antibodyFGFRL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (AA 131-160), (N-Term) antibodyFGFRL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32346 unconjugated
anti-Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (N-Term) antibodyFGFRL1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: FGFRL1-transfected 293T , HepG2 membrane extract
Validation: Orthogonal, Overexpression
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2.42 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
-
别名
- fibroblast growth factor receptor like 1
-
背景
-
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 55 kDa
-
基因ID
- 53834
-
UniProt
- Q8N441
-
途径
- RTK signaling
抗原
-
