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BACE1 抗体

This anti-BACE1 antibody is a 兔 多克隆 antibody detecting BACE1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855695
发货至: 中国

Quick Overview for BACE1 抗体 (ABIN2855695)

抗原

See all BACE1 抗体
BACE1 (Beta-secretase 1 (BACE1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BACE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to BACE1 (beta-site APP-cleaving enzyme 1)
    BACE1 antibody [N1C2]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human BACE1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000. IHC-P: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.91 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BACE1 (Beta-secretase 1 (BACE1))

    别名

    beta-secretase 1

    背景

    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.

    Cellular Localization: Membrane

    分子量

    56 kDa

    基因ID

    23621

    UniProt

    P56817
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