AKR1C4 抗体
Quick Overview for AKR1C4 抗体 (ABIN2855666)
抗原
See all AKR1C4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to HSD3a (aldo-keto reductase family 1, member C4 (chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4))
HSD3a antibody [N1C2] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human HSD3a. The exact sequence is proprietary.
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亚型
- IgG
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anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibody
AKR1C4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibodyAKR1C4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibodyAKR1C4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibodyAKR1C4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-324) antibodyAKR1C4 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (N-Term) antibodyVerified AKR1C4 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibodyAKR1C4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) antibodyAKR1C4 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) antibodyAKR1C4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.83 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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别名
- aldo-keto reductase family 1 member C4
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背景
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Cellular Localization: Cytoplasm -
分子量
- 37 kDa
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基因ID
- 1109
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UniProt
- P17516
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途径
- Steroid Hormone Biosynthesis
抗原
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