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Kallikrein 7 抗体

This anti-Kallikrein 7 antibody is a 兔 多克隆 antibody detecting Kallikrein 7 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855653
发货至: 中国

Quick Overview for Kallikrein 7 抗体 (ABIN2855653)

抗原

See all Kallikrein 7 (KLK7) 抗体
Kallikrein 7 (KLK7)

适用

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宿主

  • 83
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克隆类型

  • 86
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多克隆

标记

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This Kallikrein 7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
    KLK7 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Kallikrein 7-transfected 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.69 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

  • 抗原

    Kallikrein 7 (KLK7)

    别名

    kallikrein related peptidase 7

    背景

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

    Cellular Localization: Secreted

    分子量

    28 kDa

    基因ID

    5650

    UniProt

    P49862

    途径

    Complement System
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