VAV1 抗体 (Center)
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北京 101111
Quick Overview for VAV1 抗体 (Center) (ABIN2855640)
抗原
See all VAV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠, 大鼠, 牛
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交叉反应 （详细）
- Mouse (92 %), Rat (92 %), Bovine (96 %)
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产品特性
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Rabbit Polyclonal antibody to VAV1 (vav 1 guanine nucleotide exchange factor)
VAV1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human VAV1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody
VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 565-795) antibodyVAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (pTyr174) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (N-Term) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Vav 1 Oncogene (VAV1) (Tyr174) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 100-200) antibodyVAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (Tyr174) antibodyVAV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) antibodyVAV1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7220 unconjugated
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: Molt-4 , Raji , BCL-1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.33 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- VAV1 (Vav 1 Oncogene (VAV1))
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别名
- VAV1
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背景
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The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
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分子量
- 98 kDa
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基因ID
- 7409
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
抗原
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