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RAD23B 抗体 (Center)

This anti-RAD23B antibody is a 兔 多克隆 antibody detecting RAD23B in WB, IF, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN2855629
发货至: 中国

Quick Overview for RAD23B 抗体 (Center) (ABIN2855629)

抗原

See all RAD23B 抗体
RAD23B (RAD23 Homolog B (RAD23B))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD23B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    Center

    交叉反应

    交叉反应 (详细)

    Bovine (91 %)

    产品特性

    Rabbit Polyclonal antibody to hHR23b (RAD23 homolog B (S. cerevisiae))
    hHR23b antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human RAD23B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*

    说明

    Positive Control: 293T , A431

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.69 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    RAD23B (RAD23 Homolog B (RAD23B))

    别名

    hHR23b

    背景

    The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    Cellular Localization: Nucleus , Cytoplasm

    分子量

    43 kDa

    基因ID

    5887

    途径

    DNA Damage Repair
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