RAD23B 抗体 (Center)
Quick Overview for RAD23B 抗体 (Center) (ABIN2855629)
抗原
See all RAD23B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 牛
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交叉反应 (详细)
- Bovine (91 %)
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产品特性
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Rabbit Polyclonal antibody to hHR23b (RAD23 homolog B (S. cerevisiae))
hHR23b antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human RAD23B. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*
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说明
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Positive Control: 293T , A431
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.69 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RAD23B (RAD23 Homolog B (RAD23B))
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别名
- hHR23b
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背景
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The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Cellular Localization: Nucleus , Cytoplasm -
分子量
- 43 kDa
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基因ID
- 5887
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途径
- DNA Damage Repair
抗原
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