Lamin B1 抗体
(4 references)Quick Overview for Lamin B1 抗体 (ABIN2855607)
抗原
See all Lamin B1 (LMNB1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
交叉反应
- Hamster, 人, 小鼠
-
产品特性
-
Rabbit Polyclonal antibody to Lamin B1 (lamin B1)
Lamin B1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Lamin B1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Lamin B1 (LMNB1) (AA 397-586) antibody
LMNB1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 266-583) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 52-233) antibodyLMNB1 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Lamin B1 (LMNB1) (AA 107-186) antibodyLMNB1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Lamin B1 (LMNB1) (AA 107-186) antibodyLMNB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Lamin B1 (LMNB1) (AA 570-586), (C-Term) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 266-583) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 570-586) antibodyLMNB1 适用: 人, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 4K2 unconjugated
anti-Lamin B1 (LMNB1) (AA 361-460) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:20000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Validatio: KO/KD, Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
: "Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease." in: Nature communications, Vol. 10, Issue 1, pp. 3473, (2019) (PubMed).
: "FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops." in: Nature communications, Vol. 10, Issue 1, pp. 2253, (2019) (PubMed).
: "Crosstalk between integrin αvβ3 and ERα contributes to thyroid hormone-induced proliferation of ovarian cancer cells." in: Oncotarget, Vol. 8, Issue 15, pp. 24237-24249, (2018) (PubMed).
: "RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells." in: Nature communications, Vol. 5, pp. 5220, (2014) (PubMed).
-
: "Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease." in: Nature communications, Vol. 10, Issue 1, pp. 3473, (2019) (PubMed).
-
- Lamin B1 (LMNB1)
-
别名
- lamin B1
-
背景
-
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
Cellular Localization: Nucleus inner membrane, Lipid-anchor, Nucleoplasmic side -
分子量
- 66 kDa
-
基因ID
- 4001
-
UniProt
- P20700
-
途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
-
