MSH3 抗体 (N-Term)
Quick Overview for MSH3 抗体 (N-Term) (ABIN2855583)
抗原
See all MSH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 牛
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交叉反应 （详细）
- Bovine (83 %)
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产品特性
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Rabbit Polyclonal antibody to MSH3 (mutS homolog 3 (E. coli))
MSH3 antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human MSH3. The exact sequence is proprietary.
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亚型
- IgG
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anti-MutS Homolog 3 (MSH3) (N-Term) antibody
MSH3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 651-750) antibodyMSH3 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 521-620) antibodyMSH3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 51-100) antibodyMSH3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 617-761) antibodyMSH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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说明
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Positive Control: A549 , H1299 , HCT116
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MSH3 (MutS Homolog 3 (MSH3))
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别名
- MSH3
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背景
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Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
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分子量
- 127 kDa
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基因ID
- 4437
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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