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RANBP1 抗体

This anti-RANBP1 antibody is a 兔 多克隆 antibody detecting RANBP1 in WB, IF 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855572
发货至: 中国

Quick Overview for RANBP1 抗体 (ABIN2855572)

抗原

See all RANBP1 抗体
RANBP1 (RAN Binding Protein 1 (RANBP1))

适用

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宿主

  • 40
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克隆类型

  • 41
多克隆

标记

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This RANBP1 antibody is un-conjugated

应用范围

  • 31
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

KO Validated
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Ran BP1 (RAN binding protein 1)
    Ran BP1 antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human RanBP1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , HeLaS3 , 293T

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chao, Lai, Lu, Lin, Mai, Huang: "NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8484-98, (2012) (PubMed).

  • 抗原

    RANBP1 (RAN Binding Protein 1 (RANBP1))

    别名

    RAN binding protein 1

    背景

    Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

    分子量

    23 kDa

    基因ID

    5902

    UniProt

    P43487
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