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PDE4B 抗体

This anti-PDE4B antibody is a 兔 多克隆 antibody detecting PDE4B in ICC 和 IF. Suitable for 人.
产品编号 ABIN2855496
发货至: 中国

Quick Overview for PDE4B 抗体 (ABIN2855496)

抗原

See all PDE4B 抗体
PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

适用

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宿主

  • 33
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克隆类型

  • 32
  • 18
多克隆

标记

  • 37
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This PDE4B antibody is un-conjugated

应用范围

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Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to PDE4B (phosphodiesterase 4B, cAMP-specific)
    PDE4B antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human PDE4B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

    别名

    phosphodiesterase 4B

    背景

    This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    分子量

    83 kDa

    基因ID

    5142

    UniProt

    Q07343

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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