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ISL1 抗体

This anti-ISL1 antibody is a 兔 多克隆 antibody detecting ISL1 in WB, IF, ICC, IHC (p), IHC (fro) 和 IHC (wm). Suitable for 人.
产品编号 ABIN2855485
发货至: 中国

Quick Overview for ISL1 抗体 (ABIN2855485)

抗原

See all ISL1 抗体
ISL1 (ISL LIM Homeobox 1 (ISL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ISL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))
  • 交叉反应

    人, 小鼠, 大鼠, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to Islet 1 (ISL LIM homeobox 1)
    Islet 1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Islet 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: PC-12

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.55 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    别名

    ISL LIM homeobox 1

    背景

    This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

    Cellular Localization: Nucleus

    分子量

    39 kDa

    基因ID

    3670

    UniProt

    P61371

    途径

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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