GFR 抗体 (N-Term)
Quick Overview for GFR 抗体 (N-Term) (ABIN2855444)
抗原
See all GFR (RAPGEF5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to RAPGEF5 (Rap guanine nucleotide exchange factor (GEF) 5)
RAPGEF5 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human RAPGEF5. The exact sequence is proprietary.
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) antibody
RAPGEF5 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 201-444) antibodyRAPGEF5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (C-Term) antibodyRAPGEF5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLaS3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.74 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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别名
- Rap guanine nucleotide exchange factor 5
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背景
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Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]
Cellular Localization: Nucleus -
分子量
- 68 kDa
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基因ID
- 9771
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UniProt
- Q92565
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途径
- RTK signaling, Neurotrophin Signaling Pathway, Hepatitis C
抗原
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