CDC42BPA 抗体
Quick Overview for CDC42BPA 抗体 (ABIN2855436)
抗原
See all CDC42BPA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to MRCK alpha (CDC42 binding protein kinase alpha (DMPK-like))
MRCK alpha antibody -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MRCK alpha. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2 mg/mL
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缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
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别名
- CDC42 binding protein kinase alpha
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背景
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The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Cellular Localization: Cytoplasm (By similarity) -
分子量
- 197 kDa
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基因ID
- 8476
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UniProt
- Q5VT25
抗原
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