CDC42BPA 抗体 (Internal Region)
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- 抗原 See all CDC42BPA 抗体
- CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC42BPA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CDC42BPA Antibody detects endogenous levels of total CDC42BPA.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CDC42BPA, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDC42BPA Primary Antibody
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anti-CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA) antibody
CDC42BPA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA) antibodyCDC42BPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA) (AA 551-650) antibodyCDC42BPA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G7 unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
- 别名
- CDC42BPA (CDC42BPA 产品)
- 别名
- MRCK antibody, MRCKA antibody, PK428 antibody, Mrck antibody, Pk428 antibody, A930014J19Rik antibody, DMPK-like antibody, CDC42BPA antibody, CDC42 binding protein kinase alpha antibody, GDNF family receptor alpha 2 antibody, serine/threonine-protein kinase MRCK alpha antibody, CDC42 binding protein kinase alpha (DMPK-like) antibody, CDC42BPA antibody, Cdc42bpa antibody, GFRA2 antibody, LOC100182779 antibody, LOC100545977 antibody
- 背景
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Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9418861, PubMed:9092543). Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775). May play a role in TFRC-mediated iron uptake (PubMed:20188707). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity).
Gene: CDC42BPA
- 分子量
- 97 kDa
- 基因ID
- 8476
- UniProt
- Q5VT25
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