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GRP78 抗体 (C-Term)

The 兔 多克隆 anti-GRP78 antibody is suitable to detect GRP78 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN2855423
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRP78 抗体 (C-Term) (ABIN2855423)

抗原

See all GRP78 (HSPA5) 抗体
GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GRP78 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    交叉反应

    猕猴, 牛

    交叉反应 (详细)

    Rhesus Monkey (100 %), Bovine (100 %)

    产品特性

    Rabbit Polyclonal antibody to Grp78 (78 kDa glucose-regulated protein)
    Grp78 antibody [C2C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Grp78. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: HepG2 , NIH-3T3 , JC , BCL-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

    别名

    Grp78

    背景

    When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]

    Cellular Localization: Endoplasmic reticulum lumen , Melanosome

    分子量

    72 kDa

    基因ID

    3309

    途径

    Thyroid Hormone Synthesis, ER-Nucleus Signaling
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