PTPN12 抗体 (N-Term)
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Quick Overview for PTPN12 抗体 (N-Term) (ABIN2855422)
抗原
See all PTPN12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to PTPN12 (protein tyrosine phosphatase, non-receptor type 12)
PTPN12 antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human PTPN12. The exact sequence is proprietary.
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亚型
- IgG
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anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibody
PTPN12 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibodyPTPN12 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 682-779) antibodyPTPN12 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 539-714) antibodyPTPN12 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibodyPTPN12 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 681-714) antibodyPTPN12 适用: 人 WB 宿主: 兔 Polyclonal RB54521 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 724-756) antibodyPTPN12 适用: 人 WB 宿主: 兔 Polyclonal RB54520 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 1-780) antibodyPTPN12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 591-640) antibodyPTPN12 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 323-372) antibodyPTPN12 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.93 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
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别名
- protein tyrosine phosphatase non-receptor type 12
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背景
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Cellular Localization: Cytoplasm -
分子量
- 88 kDa
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基因ID
- 5782
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UniProt
- Q05209
抗原
-
