PTPN12 抗体 (N-Term)
Quick Overview for PTPN12 抗体 (N-Term) (ABIN2855422)
抗原
See all PTPN12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
交叉反应
- 人, 大鼠
-
产品特性
-
Rabbit Polyclonal antibody to PTPN12 (protein tyrosine phosphatase, non-receptor type 12)
PTPN12 antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human PTPN12. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibody
PTPN12 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibodyPTPN12 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 682-779) antibodyPTPN12 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 539-714) antibodyPTPN12 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) antibodyPTPN12 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 681-714) antibodyPTPN12 适用: 人 WB 宿主: 兔 Polyclonal RB54521 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 724-756) antibodyPTPN12 适用: 人 WB 宿主: 兔 Polyclonal RB54520 unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 1-780) antibodyPTPN12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 591-640) antibodyPTPN12 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase G1 (PTPN12) (AA 323-372) antibodyPTPN12 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HeLa
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.93 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
-
别名
- protein tyrosine phosphatase non-receptor type 12
-
背景
-
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Cellular Localization: Cytoplasm -
分子量
- 88 kDa
-
基因ID
- 5782
-
UniProt
- Q05209
抗原
-
