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MCAM 抗体 (N-Term)

This anti-MCAM antibody is a 兔 多克隆 antibody detecting MCAM in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855388
发货至: 中国

Quick Overview for MCAM 抗体 (N-Term) (ABIN2855388)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

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    N-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to CD146 (melanoma cell adhesion molecule)
    CD146 antibody [N1N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human CD146. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A375 , HeLa

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    melanoma cell adhesion molecule

    背景

    Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

    分子量

    72 kDa

    基因ID

    4162

    UniProt

    P43121
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