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AIF 抗体 (N-Term)

This anti-AIF antibody is a 兔 多克隆 antibody detecting AIF in WB, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN2855383
发货至: 中国

Quick Overview for AIF 抗体 (N-Term) (ABIN2855383)

抗原

See all AIF (AIFM1) 抗体
AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This AIF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    N-Term

    产品特性

    Rabbit Polyclonal antibody to AIF (apoptosis-inducing factor, mitochondrion-associated, 1)
    AIF antibody [N1N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human AIF. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , A375

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.72 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

    别名

    AIF

    背景

    This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.

    Cellular Localization: Mitochondrion intermembrane space , Nucleus

    分子量

    67 kDa

    基因ID

    9131

    途径

    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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