AIF 抗体 (N-Term)
Quick Overview for AIF 抗体 (N-Term) (ABIN2855383)
抗原
See all AIF (AIFM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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产品特性
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Rabbit Polyclonal antibody to AIF (apoptosis-inducing factor, mitochondrion-associated, 1)
AIF antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human AIF. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , A375
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.72 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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别名
- AIF
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背景
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This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.
Cellular Localization: Mitochondrion intermembrane space , Nucleus -
分子量
- 67 kDa
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基因ID
- 9131
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
抗原
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