CARD8 抗体 (C-Term)
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Quick Overview for CARD8 抗体 (C-Term) (ABIN2855381)
抗原
See all CARD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to CARD8 (caspase recruitment domain family, member 8)
CARD8 antibody [N3C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human CARD8. The exact sequence is proprietary.
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibody
CARD8 适用: 人 WB, ICC, IP, FACS, DB 宿主: 小鼠 Monoclonal 2108C2a unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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别名
- caspase recruitment domain family member 8
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背景
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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 49 kDa
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基因ID
- 22900
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UniProt
- Q9Y2G2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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