NXF1 抗体 (C-Term)
Quick Overview for NXF1 抗体 (C-Term) (ABIN2855276)
抗原
See all NXF1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            序列
- CSSGALDYDI PTTASENLYF Q
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                                            交叉反应
- 人, 小鼠
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                                            产品特性
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                        Rabbit Polyclonal antibody to TAP (nuclear RNA export factor 1)
 TAP antibody [C2C3], C-term
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                                            纯化方法
- Affinity purified by Protein A.
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                                            免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human TAP. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: Mouse brain , A431 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 10.00 mg/mL
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                                            缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - NXF1 (Nuclear RNA Export Factor 1 (NXF1))
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                                            别名
- nuclear RNA export factor 1
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                                            背景
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                        This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. 
 Cellular Localization: Nucleus , nucleoplasm , Nucleus speckle , Cytoplasm
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                                            分子量
- 70 kDa
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                                            基因ID
- 10482
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                                            UniProt
- Q9UBU9
 抗原
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