PSMA7 抗体 (Center)
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北京 101111
Quick Overview for PSMA7 抗体 (Center) (ABIN2855151)
抗原
See all PSMA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鸡, 猪, 大鼠, 牛, Xenopus tropicalis
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交叉反应 （详细）
- Chicken (96 %), Pig (98 %), Rat (98 %), Bovine (99 %), Xenopus tropicalis (97 %)
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产品特性
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Rabbit Polyclonal antibody to PSMA7 (proteasome (prosome, macropain) subunit, alpha type, 7)
PSMA7 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Proteasome 20S alpha 7. The exact sequence is proprietary.
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亚型
- IgG
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anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibody
PSMA7 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1A10-3G12 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibodyPSMA7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 5-232) antibodyPSMA7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibodyPSMA7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1605 unconjugated Recombinant Antibody
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人 WB, IHC, FACS 宿主: 小鼠 Monoclonal 3F11 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 3-211) antibodyPSMA7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (Internal Region) antibodyPSMA7 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.32 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
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别名
- PSMA7
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背景
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 28 kDa
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基因ID
- 5688
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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