HGS 抗体 (C-Term)
Quick Overview for HGS 抗体 (C-Term) (ABIN2855140)
抗原
See all HGS 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
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                        Rabbit Polyclonal antibody to HGS (hepatocyte growth factor-regulated tyrosine kinase substrate)
 HGS antibody [C2C3], C-term
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human HGS. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Validation: Orthogonal 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
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                                            别名
- hepatocyte growth factor-regulated tyrosine kinase substrate
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                                            背景
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                        The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. 
 Cellular Localization: Cytoplasm , Early endosome membrane, Peripheral membrane protein, Cytoplasmic side , Endosome , multivesicular body membrane, Peripheral membrane protein
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                                            分子量
- 86 kDa
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                                            基因ID
- 9146
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                                            UniProt
- O14964
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                                            途径
- EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
 抗原
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