LGALS1/Galectin 1 抗体
Quick Overview for LGALS1/Galectin 1 抗体 (ABIN2855093)
抗原
See all LGALS1/Galectin 1 (LGALS1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Galectin 1 (lectin, galactoside-binding, soluble, 1)
Galectin 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Galectin 1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NCI-H929 , BCL-1 , PC-12 , Rat2 , HeLa
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.52 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics." in: Frontiers in immunology, Vol. 11, pp. 1316, (2020) (PubMed).
: "Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 67, (2019) (PubMed).
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: "Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics." in: Frontiers in immunology, Vol. 11, pp. 1316, (2020) (PubMed).
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- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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别名
- galectin 1
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背景
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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
Cellular Localization: Secreted , extracellular space , extracellular matrix -
分子量
- 15 kDa
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基因ID
- 3956
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UniProt
- P09382
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途径
- Carbohydrate Homeostasis
抗原
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