Prothrombin 抗体 (N-Term)
Quick Overview for Prothrombin 抗体 (N-Term) (ABIN2854967)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Prothrombin (coagulation factor II (thrombin))
Prothrombin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human Prothrombin. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , human plasma , mouse plasma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- coagulation factor II, thrombin
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背景
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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
Cellular Localization: Secreted , extracellular space -
分子量
- 70 kDa
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基因ID
- 2147
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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