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Glucocorticoid Receptor 抗体 (N-Term)

Name: Glucocorticoid Receptor 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN2854939
Availability: OutOfStock

This anti-Glucocorticoid Receptor antibody is a 兔多克隆 antibody detecting Glucocorticoid Receptor in WB, IF, IP, ICC 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

WB Image Glucocorticoid receptor antibody detects Glucocorticoid receptor protein by western blot analysis. (Glucocorticoid Receptor 抗体 (N-Term))

IHC-P Image Immunohistochemical analysis of paraffin-embedded Hela xenograft, using Glucocorticoid receptor, antibody at 1:500 dilution. (Glucocorticoid Receptor 抗体 (N-Term))

IHC

WB Image Sample (30 ug of whole cell lysate) A: A431 , 7. (Glucocorticoid Receptor 抗体 (N-Term))

IP Image Glucocorticoid receptor antibody immunoprecipitates Glucocorticoid receptor protein in IP experiments. (Glucocorticoid Receptor 抗体 (N-Term))

5 images

(2 references)

产品编号 ABIN2854939

发货至: 中国

Quick Overview for Glucocorticoid Receptor 抗体 (N-Term) (ABIN2854939)

抗原

See all Glucocorticoid Receptor (NR3C1) 抗体

Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This Glucocorticoid Receptor antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated

Discover our top product NR3C1 Primary Antibody

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N-Term

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to Glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor))
Glucocorticoid receptor antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the N-terminus region of human Glucocorticoid Receptor. The exact sequence is proprietary.

亚型

IgG
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-280) antibody
NR3C1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 51-140) antibody
NR3C1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C8 unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody
NR3C1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E6 unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 231-320) antibody
NR3C1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 598-755) antibody
NR3C1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (Ser211) antibody
NR3C1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-190) antibody
NR3C1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-373) antibody
NR3C1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (pSer211) antibody
NR3C1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (Ser226), (Ser234), (Ser246) antibody
NR3C1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: A431 , mouse heart , rat heart , HeLa
Validation: KO/KD

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Bolt, Stossi, Callison, Mancini, Dandekar, Mancini: "Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity." in: Oncogene, Vol. 34, Issue 2, pp. 154-64, (2015) (PubMed).

Bolt, Stossi, Newberg, Orjalo, Johansson, Mancini: "Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4036-48, (2013) (PubMed).
抗原

Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

别名

nuclear receptor subfamily 3 group C member 1

背景

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.

Cellular Localization: Cytoplasm , Nucleus

分子量

86 kDa

基因ID

2908

UniProt

P04150

途径

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process