Amphiregulin 抗体
(2 references)-
- 抗原 See all Amphiregulin (AREG) 抗体
- Amphiregulin (AREG)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Amphiregulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to Amphiregulin (amphiregulin)
Amphiregulin antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Amphiregulin. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Amphiregulin (AREG) (AA 20-100) antibody
AREG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A5 unconjugated
anti-Amphiregulin (AREG) (AA 185-252) antibodyAREG 适用: 人, 小鼠, 大鼠, 豚鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-252) antibodyAREG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 107-148) antibodyAREG 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) antibodyAREG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-100) antibodyAREG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 97-243) antibodyAREG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 222-252), (C-Term) antibodyAREG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14426 unconjugated
anti-Amphiregulin (AREG) (AA 94-191) antibodyAREG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 27-247) antibodyAREG 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: AREG-transfected 293T
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.17 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG." in: International journal of molecular medicine, Vol. 45, Issue 4, pp. 1163-1175, (2020) (PubMed).
: "The impact of co-expression of wild-type EGFR and its ligands determined by immunohistochemistry for response to treatment with cetuximab in patients with metastatic colorectal cancer." in: Oncotarget, Vol. 8, Issue 5, pp. 7666-7677, (2018) (PubMed).
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: "Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG." in: International journal of molecular medicine, Vol. 45, Issue 4, pp. 1163-1175, (2020) (PubMed).
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- 抗原
- Amphiregulin (AREG)
- 别名
- amphiregulin (AREG 产品)
- 别名
- AR antibody, CRDGF antibody, SDGF antibody, Sdgf antibody, AREG antibody, AREGB antibody, AREG/SDGF antibody, amphiregulin antibody, AREG antibody, Areg antibody
- 背景
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The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Cellular Localization: Membrane - 分子量
- 28 kDa
- 基因ID
- 374
- UniProt
- P15514
- 途径
- RTK signaling, EGFR Signaling Pathway
