Amphiregulin 抗体
(2 references)Quick Overview for Amphiregulin 抗体 (ABIN2854897)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Amphiregulin (amphiregulin)
Amphiregulin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Amphiregulin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Amphiregulin (AREG) (AA 185-252) antibody
AREG 适用: 人, 小鼠, 大鼠, 豚鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-100) antibodyAREG 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Amphiregulin (AREG) (AA 20-252) antibodyAREG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-129) antibodyAREG 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Amphiregulin (AREG) (AA 107-148) antibodyAREG 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-100) antibodyAREG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 97-243) antibodyAREG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 94-191) antibodyAREG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 27-247) antibodyAREG 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 1-252) antibodyAREG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: AREG-transfected 293T
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.17 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG." in: International journal of molecular medicine, Vol. 45, Issue 4, pp. 1163-1175, (2020) (PubMed).
: "The impact of co-expression of wild-type EGFR and its ligands determined by immunohistochemistry for response to treatment with cetuximab in patients with metastatic colorectal cancer." in: Oncotarget, Vol. 8, Issue 5, pp. 7666-7677, (2018) (PubMed).
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: "Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG." in: International journal of molecular medicine, Vol. 45, Issue 4, pp. 1163-1175, (2020) (PubMed).
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- Amphiregulin (AREG)
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别名
- amphiregulin
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背景
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The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Cellular Localization: Membrane -
分子量
- 28 kDa
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基因ID
- 374
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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