Crk 抗体 (Center)
Quick Overview for Crk 抗体 (Center) (ABIN2854888)
抗原
See all Crk (CRK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 牛
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交叉反应 （详细）
- Bovine (100 %)
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产品特性
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Rabbit Polyclonal antibody to CRK (v-crk sarcoma virus CT10 oncogene homolog (avian))
CRK antibody [N2C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CRK. The exact sequence is proprietary.
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亚型
- IgG
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anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) antibody
CRK 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3G11C1 unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibodyCRK 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibodyCRK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 2-246) antibodyCRK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibodyCRK 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 122-302) antibodyCRK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibodyCRK 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 40-196) antibodyCRK 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) antibodyCRK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-304) antibodyCRK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 293T , A431 , H1299 , HepG2 , Raji , NIH-3T3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
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别名
- CRK
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背景
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This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
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分子量
- 34 kDa
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基因ID
- 1398
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途径
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
抗原
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