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BMP4 抗体

Name: BMP4 抗体
Brand: antibodies-online
SKU: ABIN2854883
Availability: OutOfStock

This anti-BMP4 antibody is a 兔多克隆 antibody detecting BMP4 in WB, ICC, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC 10% SDS PAGE antibody diluted at 1:1000 (BMP4 抗体)

ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using BMP4, antibody at 1:100 dilution. (BMP4 抗体)

WB Image BMP4 antibody detects BMP4 protein by Western blot analysis. (BMP4 抗体)

IHC-P Image Immunohistochemical analysis of paraffin-embedded MDA-MB468 xenograft, using BMP4, antibody at 1:100 dilution. (BMP4 抗体)

IHC

TSA rescues BMP expression in SKPs. (BMP4 抗体)

IF (cc)

BMP4 expression is elevated during Oleic acid-induced triglyceride/lipid accumulation in hepatocytes and in a mouse model of NAFLD. (BMP4 抗体)

9 images

(2 references)

产品编号 ABIN2854883

发货至: 中国

Datasheet as PDF

Quick Overview for BMP4 抗体 (ABIN2854883)

抗原

See all BMP4 抗体

BMP4 (Bone Morphogenetic Protein 4 (BMP4))

适用

人

宿主

兔

克隆类型

多克隆

标记

This BMP4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product BMP4 Primary Antibody

特异性

This antibody is able to recognize full length BMP4 protein (~55 kDa) and N-terminal propeptide BMP4 protein (~40 kDa) but unable to detect mature form.

交叉反应

人, 小鼠

产品特性

Rabbit Polyclonal antibody to BMP4 (bone morphogenetic protein 4)
BMP4 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human BMP4. The exact sequence is proprietary.

亚型

IgG
anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibody
BMP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibody
BMP4 适用: 人, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C11C7 unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibody
BMP4 适用: 人, 大鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3C11H8 unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibody
BMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibody
BMP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibody
BMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibody
BMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibody (APC)
BMP4 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC

anti-Bone Morphogenetic Protein 4 (BMP4) antibody
BMP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Bone Morphogenetic Protein 4 (BMP4) (AA 25-408) antibody
BMP4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal PA354-16-1-1 unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: NIH-3T3 , JC , HepG2 conditioned medium
Validation: Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.36 mg/mL

缓冲液

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Guo, Wang, Yuan, Zhu, Fu, Xu, Wu, Wu: "TSA restores hair follicle-inductive capacity of skin-derived precursors." in: Scientific reports, Vol. 9, Issue 1, pp. 2867, (2020) (PubMed).

Peng, Chen, Wang, Zhu, Wu, Luo, Zuo, Luo, Zhou, Shi, Weng, Huang, He, Fan: "Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes." in: Aging, Vol. 11, Issue 23, pp. 11520-11540, (2019) (PubMed).
抗原

BMP4 (Bone Morphogenetic Protein 4 (BMP4))

别名

bone morphogenetic protein 4

背景

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Cellular Localization: Secreted , extracellular space , extracellular matrix

分子量

47 kDa

基因ID

652

UniProt

P12644

途径

Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development