BMP4 抗体
(2 references)-
- 抗原 See all BMP4 抗体
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BMP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody is able to recognize full length BMP4 protein (~55 kDa) and N-terminal propeptide BMP4 protein (~40 kDa) but unable to detect mature form.
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to BMP4 (bone morphogenetic protein 4)
BMP4 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human BMP4. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product BMP4 Primary Antibody
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anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibody
BMP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C11C7 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3C11H8 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibodyBMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibodyBMP4 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 25-408) antibodyBMP4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal PA354-16-1-1 unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: NIH-3T3 , JC , HepG2 conditioned medium
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.36 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "TSA restores hair follicle-inductive capacity of skin-derived precursors." in: Scientific reports, Vol. 9, Issue 1, pp. 2867, (2020) (PubMed).
: "Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes." in: Aging, Vol. 11, Issue 23, pp. 11520-11540, (2019) (PubMed).
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: "TSA restores hair follicle-inductive capacity of skin-derived precursors." in: Scientific reports, Vol. 9, Issue 1, pp. 2867, (2020) (PubMed).
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- 抗原
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
- 别名
- bone morphogenetic protein 4 (BMP4 产品)
- 背景
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The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Cellular Localization: Secreted , extracellular space , extracellular matrix - 分子量
- 47 kDa
- 基因ID
- 652
- UniProt
- P12644
- 途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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