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RPSA/Laminin Receptor 抗体

This anti-RPSA/Laminin Receptor antibody is a 兔 多克隆 antibody detecting RPSA/Laminin Receptor in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854873
发货至: 中国

Quick Overview for RPSA/Laminin Receptor 抗体 (ABIN2854873)

抗原

See all RPSA/Laminin Receptor (RPSA) 抗体
RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

适用

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宿主

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克隆类型

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多克隆

标记

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This RPSA/Laminin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to RPSA (ribosomal protein SA)
    RPSA antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human RPSA. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , Jurkat , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

    别名

    ribosomal protein SA

    背景

    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cell membrane , Cytoplasm (By similarity) , Nucleus (By similarity)

    分子量

    33 kDa

    基因ID

    3921

    UniProt

    P08865

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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