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CD11b 抗体 (Center)

The 兔 多克隆 anti-CD11b antibody (ABIN2854872) specifically detects CD11b in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2854872
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD11b 抗体 (Center) (ABIN2854872)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Center

    产品特性

    Rabbit Polyclonal antibody to CD11b (integrin, alpha M (complement component 3 receptor 3 subunit))
    CD11b antibody [C1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CD11b. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: THP-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    分子量

    127 kDa

    基因ID

    3684

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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