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TLR9 抗体 (N-Term)

This anti-TLR9 antibody is a 兔 多克隆 antibody detecting TLR9 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854849
发货至: 中国

Quick Overview for TLR9 抗体 (N-Term) (ABIN2854849)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to TLR9 (toll-like receptor 9)
    TLR9 antibody [N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TLR9. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: THP-1 , TLR9 transfected 293T

    Validation: Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.4 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    别名

    toll like receptor 9

    背景

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    分子量

    116 kDa

    基因ID

    54106

    UniProt

    Q9NR96

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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