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HDAC6 抗体 (N-Term)

This anti-HDAC6 antibody is a 兔 多克隆 antibody detecting HDAC6 in WB, IF, IHC (p), ICC 和 FACS. Suitable for 人.
产品编号 ABIN2854846
发货至: 中国

Quick Overview for HDAC6 抗体 (N-Term) (ABIN2854846)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)
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    N-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to HDAC6 (histone deacetylase 6)
    HDAC6 antibody [N1], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HDAC6. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 3xFlag-human HDAC6-transfected 293T

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.18 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    histone deacetylase 6

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

    Cellular Localization: Nucleus , Cytoplasm

    分子量

    131 kDa

    基因ID

    10013

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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