SOD1 抗体 (C-Term)
Quick Overview for SOD1 抗体 (C-Term) (ABIN2854826)
抗原
See all SOD1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
SOD1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOD1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Rat brain , 293T , A431 , HeLa , HepG2
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.21 mg/mL
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缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
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: "Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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别名
- superoxide dismutase 1
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背景
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The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Cellular Localization: Cytoplasm -
分子量
- 16 kDa
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基因ID
- 6647
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UniProt
- P00441
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
抗原
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