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SOD1 抗体 (C-Term)

Cited in 1 publication. This 兔 多克隆 anti-SOD1 antibody specifically detects SOD1 in WB 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN2854826
发货至: 中国
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Quick Overview for SOD1 抗体 (C-Term) (ABIN2854826)

抗原

See all SOD1 抗体
SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SOD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
    SOD1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOD1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Rat brain , 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.21 mg/mL

    缓冲液

    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chang, Fong, Tsai, Chang, Chou, Wu, Teng, Liu, Yuan, Chiu: "Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

  • 抗原

    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

    别名

    superoxide dismutase 1

    背景

    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

    Cellular Localization: Cytoplasm

    分子量

    16 kDa

    基因ID

    6647

    UniProt

    P00441

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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