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MTDH 抗体

This anti-MTDH antibody is a 兔 多克隆 antibody detecting MTDH in WB, IF, IHC (p) 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854801
发货至: 中国

Quick Overview for MTDH 抗体 (ABIN2854801)

抗原

See all MTDH 抗体
MTDH (Metadherin (MTDH))

适用

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宿主

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克隆类型

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多克隆

标记

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This MTDH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit polyclonal antibody to LYRIC (metadherin)
    LYRIC antibody [N2C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.69 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lai, Chuang, Liu, Ho, Lin, Anderson, Yeh: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." in: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).

  • 抗原

    MTDH (Metadherin (MTDH))

    别名

    metadherin

    背景

    Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

    Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region

    分子量

    64 kDa

    基因ID

    92140

    UniProt

    Q86UE4

    途径

    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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