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TARDBP 抗体

The 兔 多克隆 anti-TARDBP antibody is suitable to detect TARDBP in samples from 人. It has been validated for WB, IF, ICC 和 IHC (p).
产品编号 ABIN2854799
发货至: 中国
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Quick Overview for TARDBP 抗体 (ABIN2854799)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TARDBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to TARDBP (TAR DNA binding protein)
    TARDBP antibody

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299 , HeLa , mouse brain

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TAR DNA binding protein

    背景

    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

    Cellular Localization: Nucleus

    分子量

    45 kDa

    基因ID

    23435

    UniProt

    Q13148

    途径

    Positive Regulation of Peptide Hormone Secretion
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