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SOD1 抗体

Name: SOD1 抗体
Brand: antibodies-online
SKU: ABIN2854793
Availability: OutOfStock

This anti-SOD1 antibody is a 兔多克隆 antibody detecting SOD1 in WB, ELISA 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 5+ publications.

WB Image Sample (50 ug of whole cell lysate) A: Rat brain 15% SDS PAGE antibody diluted at 1:1000 (SOD1 抗体)

IHC Image SOD1 antibody detects SOD1 protein at cytosol on mouse fore brain by immunohistochemical analysis. (SOD1 抗体)

IHC

WB Image SOD1 antibody detects SOD1 protein by western blot analysis. (SOD1 抗体)

WB Image Sample (50 ug of whole cell lysate) A: mouse brain 15% SDS PAGE antibody diluted at 1:1000 (SOD1 抗体)

WB Image Western blot analysis of SOD1 (, upper panel) and beta-actin , lower panel) Sample (10 ug of whole cell lysate) A: HeLa mock control B: HeLa transfected shSOD1 15% SDS PAGE antibody diluted at 1:500 (SOD1 抗体)

WB Image Sample (30 ug of whole cell lysate) A: Hela 15% SDS PAGE Superoxide Dismutase 1 antibody antibody diluted at 1:1000 (SOD1 抗体)

ELISA

8 images

(5 references)

产品编号 ABIN2854793

发货至: 中国

Quick Overview for SOD1 抗体 (ABIN2854793)

抗原

See all SOD1 抗体

SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SOD1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated

Discover our top product SOD1 Primary Antibody

交叉反应

Alligator, Avian, 人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
SOD1 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.

亚型

IgG
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 1-154) antibody
SOD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibody
KO Validated SOD1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 人, 马 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibody
SOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody (APC)
SOD1 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody
SOD1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) antibody
SOD1 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F5 unconjugated

应用备注

WB: 1:500-1:10000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: mouse brain , Rat brain , NT2D1 , 293T
Validation: KO/KD, Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.15 mg/mL

缓冲液

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Balhorn, Hartmann, Schupp: "Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys." in: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).

Parry, Kephart, Mumford, Romero, Mobley, Zhang, Roberts, Kavazis: "Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats." in: Heliyon, Vol. 4, Issue 11, pp. e00975, (2018) (PubMed).

Gentile, Fornai, Pellegrini, Colucci, Benvenuti, Duranti, Masi, Carpi, Nieri, Nericcio, Garelli, Virdis, Pistelli, Blandizzi, Antonioli: "Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity." in: Frontiers in pharmacology, Vol. 9, pp. 1094, (2018) (PubMed).

Mowry, Kavazis, Sirman, Potts, Hood: "Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160883, (2017) (PubMed).

Brand, Amann, Mandel, Zimnol, Schupp: "Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors." in: PLoS ONE, Vol. 9, Issue 12, pp. e115715, (2015) (PubMed).
抗原

SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

别名

superoxide dismutase 1

背景

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Cellular Localization: Cytoplasm

分子量

16 kDa

基因ID

6647

UniProt

P00441

途径

Sensory Perception of Sound, Transition Metal Ion Homeostasis