ABAT 抗体
Quick Overview for ABAT 抗体 (ABIN2854765)
抗原
See all ABAT 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to ABAT (4-aminobutyrate aminotransferase)
ABAT antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ABAT. The exact sequence is proprietary.
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亚型
- IgG
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anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 236-500) antibody
ABAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 151-250) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 1-500) antibodyABAT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (C-Term) antibodyABAT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (Internal Region) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 249-500) antibodyABAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 5B6 unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: SK-N-SH , mouse brain , rat brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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别名
- 4-aminobutyrate aminotransferase
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背景
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4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Cellular Localization: Mitochondrion matrix -
分子量
- 56 kDa
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基因ID
- 18
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UniProt
- P80404
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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