MMP 9 抗体
-
- 抗原 See all MMP 9 (MMP9) 抗体
- MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MMP 9 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))
- 交叉反应
- Cow, 人, 小鼠, 大鼠
- 产品特性
-
Rabbit Polyclonal antibody to MMP9 (matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase))
MMP9 antibody [N2C1], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human MMP9. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product MMP9 Primary Antibody
-
-
- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Validation: Orthogonal
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.88 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population." in: Cells, Vol. 9, Issue 8, (2020) (PubMed).
: "Antitumor effect of kurarinone and underlying mechanism in small cell lung carcinoma cells." in: OncoTargets and therapy, Vol. 12, pp. 6119-6131, (2019) (PubMed).
: "The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity." in: Scientific reports, Vol. 8, Issue 1, pp. 12995, (2019) (PubMed).
: "Senescent tumor cells lead the collective invasion in thyroid cancer." in: Nature communications, Vol. 8, pp. 15208, (2018) (PubMed).
: "The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1." in: Scientific reports, Vol. 6, pp. 19874, (2016) (PubMed).
: "
-
Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population." in: Cells, Vol. 9, Issue 8, (2020) (PubMed).
-
- 抗原
- MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
- 别名
- matrix metallopeptidase 9 (MMP9 产品)
- 背景
-
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Cellular Localization: Secreted , extracellular space , extracellular matrix - 分子量
- 78 kDa
- 基因ID
- 4318
- UniProt
- P14780
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events
-