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MMP 9 抗体 (N-Term)

MMP9 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 斑马鱼, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777743
发货至: 中国
  • 抗原 See all MMP 9 (MMP9) 抗体
    MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
    抗原表位
    • 16
    • 15
    • 15
    • 12
    • 11
    • 11
    • 8
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    • 6
    • 6
    • 5
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 149
    • 84
    • 66
    • 35
    • 18
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 斑马鱼, 豚鼠, 绵羊
    宿主
    • 152
    • 47
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 139
    • 64
    多克隆
    标记
    • 91
    • 20
    • 14
    • 12
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MMP 9 antibody is un-conjugated
    应用范围
    • 163
    • 71
    • 59
    • 40
    • 40
    • 36
    • 34
    • 34
    • 32
    • 32
    • 13
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    VAEHGDGYPF DGKDGLLAHA FPPGPGIQGD AHFDDDELWS LGKGVVVPTR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against MMP9. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MMP9
    Top Product
    Discover our top product MMP9 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 707 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Puttabyatappa, Irwin, Martin, Mesquitta, Veiga-Lopez, Padmanabhan: "Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins" in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697130, (2017) (PubMed).

    Strilakou, Perelas, Lazaris, Papavdi, Karkalousos, Giannopoulou, Kriebardis, Panayiotides, Liapi: "Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine." in: Fundamental & clinical pharmacology, Vol. 30, Issue 1, pp. 47-57, (2016) (PubMed).

    Zhang, Jiang, Zuo: "Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB." in: Neuroscience, Vol. 261, pp. 1-10, (2014) (PubMed).

    Li, Tan, Zhang, Han, Di, Xiao, Cheng, Gao, Liu: "DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling." in: PLoS ONE, Vol. 9, Issue 3, pp. e91509, (2014) (PubMed).

    Deng, Zhang, Feng, Xiong, Zuo: "Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice†." in: Cardiovascular research, Vol. 103, Issue 4, pp. 473-84, (2014) (PubMed).

    Gotschy, Bauer, Schrodt, Lykowsky, Ye, Rommel, Jakob, Bauer, Herold: "Local arterial stiffening assessed by MRI precedes atherosclerotic plaque formation." in: Circulation. Cardiovascular imaging, Vol. 6, Issue 6, pp. 916-23, (2013) (PubMed).

  • 抗原
    MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
    别名
    MMP9 (MMP9 产品)
    别名
    CLG4B antibody, GELB antibody, MANDP2 antibody, MMP-9 antibody, AW743869 antibody, B/MMP9 antibody, Clg4b antibody, pro-MMP-9 antibody, mmp-9 antibody, fgMMP-9 antibody, mmp9 antibody, ZFMMP-9 antibody, wu:fb02g06 antibody, wu:fb07b05 antibody, wu:fi98c09 antibody, wu:fj05a08 antibody, zgc:64165 antibody, clg4b antibody, gelb antibody, mandp2 antibody, matrix metallopeptidase 9 antibody, collagenase antibody, matrix metalloproteinase 9 antibody, matrix metallopeptidase 9 S homeolog antibody, MMP9 antibody, RB3913 antibody, BPSS0666 antibody, Sbal_3732 antibody, Bcer98_0486 antibody, Shew185_0630 antibody, Shal_3056 antibody, Sbal195_0657 antibody, Lbys_3550 antibody, Palpr_2084 antibody, Mmp9 antibody, mmp9 antibody, mmp9.S antibody
    背景
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
    Alias Symbols: GELB, CLG4B, MMP-9, MANDP2
    Protein Interaction Partner: CXCL5, PZP, MMP26, RECK, KISS1, PRSS2, EPHB2, BTC, LCN2, COL4A6, COL4A5, TIMP3, THBS2, THBS1, MMP10, MMP7, PLG, CXCL1, TFPI, CXCL8, FN1, MMP9, COL1A2, COL1A1, COL4A4, COL4A1, COL4A2, COL4A3, HAPLN1, CD44, AREG, TGFB1, CXCL6,
    Protein Size: 707
    分子量
    78 kDa
    基因ID
    4318
    NCBI登录号
    NM_004994, NP_004985
    UniProt
    P14780
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events
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