POLG 抗体 (C-Term)
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北京 101111
Quick Overview for POLG 抗体 (C-Term) (ABIN2854742)
抗原
See all POLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
DNA polymerase gamma antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DNA polymerase gamma. The exact sequence is proprietary.
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亚型
- IgG
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anti-Polymerase (DNA Directed), gamma (POLG) (AA 1101-1239) antibody
POLG 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 1041-1239) antibodyPOLG 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) antibodyPOLG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 1120-1148), (C-Term) antibodyPOLG 适用: 人, 小鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 446-590) antibodyPOLG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) antibodyKD Validated POLG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1085 unconjugated Recombinant Antibody
anti-Polymerase (DNA Directed), gamma (POLG) (AA 242-291) antibodyPOLG 适用: 人, 小鼠, 大鼠, Cow, Bat, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (N-Term) antibodyPOLG 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (N-Term) antibodyPOLG 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Rat testis , MCF-7 , MDA-MB-231
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.67 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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别名
- DNA polymerase gamma
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背景
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Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Mitochondrion -
分子量
- 140 kDa
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基因ID
- 5428
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UniProt
- P54098
抗原
-
