CXCR1 抗体 (C-Term)
Quick Overview for CXCR1 抗体 (C-Term) (ABIN2854740)
抗原
See all CXCR1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- C-Term
-
交叉反应
- 人, 小鼠
-
产品特性
-
Rabbit Polyclonal antibody to CXCR1 (chemokine (C-X-C motif) receptor 1)
CXCR1 antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCR1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Validation: KO/KD
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.97 mg/mL
-
缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
-
别名
- C-X-C motif chemokine receptor 1
-
背景
-
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Cellular Localization: Cell membrane -
分子量
- 40 kDa
-
基因ID
- 3577
-
UniProt
- P25024
-
途径
- cAMP Metabolic Process
抗原
-