HTR2C 抗体 (C-Term)
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北京 101111
Quick Overview for HTR2C 抗体 (C-Term) (ABIN2854715)
抗原
See all HTR2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to 5-HT2C receptor
5-HT2C receptor antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 5-HT2C receptor. The exact sequence is proprietary.
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亚型
- IgG
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anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (N-Term) antibody
HTR2C 适用: 人, 小鼠, 大鼠, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Internal Region) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 387-446) antibodyHTR2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) antibodyHTR2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 9H8 unconjugated Recombinant Antibody
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) antibodyHTR2C 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2025 unconjugated Recombinant Antibody
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Cytoplasmic Domain) antibodyHTR2C 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 1-52) antibodyHTR2C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 243-256), (Extracellular) antibodyHTR2C 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 311-410) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 274-308) antibodyHTR2C 适用: 人 WB 宿主: 兔 Polyclonal RB52766 unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: rat brain , mouse placenta
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.68 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
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别名
- 5-hydroxytryptamine receptor 2C
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背景
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Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims.
Cellular Localization: Cell membrane -
分子量
- 52 kDa
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基因ID
- 3358
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UniProt
- P28335
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
抗原
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