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IL13 Receptor alpha 1 抗体

This anti-IL13 Receptor alpha 1 antibody is a 兔 多克隆 antibody detecting IL13 Receptor alpha 1 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854528
发货至: 中国

Quick Overview for IL13 Receptor alpha 1 抗体 (ABIN2854528)

抗原

See all IL13 Receptor alpha 1 (IL13RA1) 抗体
IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

适用

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宿主

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克隆类型

  • 60
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多克隆

标记

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This IL13 Receptor alpha 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to IL13 Receptor alpha 1 (interleukin 13 receptor, alpha 1)
    IL13 Receptor alpha 1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human IL13 Receptor alpha 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG , U87-MG membrane extract , IL13RA1-transfected 293T

    Validation: Orthogonal, Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.51 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ding, Jin, Xie, Park, Tong, Wu, Chhabra, Fu, Li: "A Murine Model for Human ECO Syndrome Reveals a Critical Role of Intestinal Cell Kinase in Skeletal Development." in: Calcified tissue international, Vol. 102, Issue 3, pp. 348-357, (2019) (PubMed).

  • 抗原

    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

    别名

    interleukin 13 receptor subunit alpha 1

    背景

    The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    分子量

    49 kDa

    基因ID

    3597

    UniProt

    P78552

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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