IL13 Receptor alpha 1 抗体
(1 reference)Quick Overview for IL13 Receptor alpha 1 抗体 (ABIN2854528)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to IL13 Receptor alpha 1 (interleukin 13 receptor, alpha 1)
IL13 Receptor alpha 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human IL13 Receptor alpha 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 22-343) antibody
IL13RA1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A3E3 unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibodyIL13RA1 适用: 人 ELISA, FACS, cELISA, Anta 宿主: 小鼠 Monoclonal GM-1E7 unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 203-376) antibodyIL13RA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 1-427) antibodyIL13RA1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (C-Term) antibodyIL13RA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 371-420) antibodyIL13RA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 22-234) antibodyIL13RA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) antibodyIL13RA1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 1-427) antibodyIL13RA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 22-343) antibodyIL13RA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , U87-MG membrane extract , IL13RA1-transfected 293T
Validation: Orthogonal, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.51 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "A Murine Model for Human ECO Syndrome Reveals a Critical Role of Intestinal Cell Kinase in Skeletal Development." in: Calcified tissue international, Vol. 102, Issue 3, pp. 348-357, (2019) (PubMed).
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: "A Murine Model for Human ECO Syndrome Reveals a Critical Role of Intestinal Cell Kinase in Skeletal Development." in: Calcified tissue international, Vol. 102, Issue 3, pp. 348-357, (2019) (PubMed).
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
- interleukin 13 receptor subunit alpha 1
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背景
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The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 49 kDa
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基因ID
- 3597
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UniProt
- P78552
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
-
