ATF6 抗体 (C-Term)
Quick Overview for ATF6 抗体 (C-Term) (ABIN2854487)
抗原
See all ATF6 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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特异性
- This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form.,Knockdown/Knockout validation was supported by references (PMID:29535165)
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to ATF6 (activating transcription factor 6)
ATF6 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF6. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Validatio: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
: "
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Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
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- ATF6 (Activating Transcription Factor 6 (ATF6))
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别名
- activating transcription factor 6
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背景
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ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]
Cellular Localization: Endoplasmic reticulum membrane , Processed cyclic AMP-dependent transcription factor ATF-6 alpha: Nucleus -
分子量
- 75 kDa
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基因ID
- 22926
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UniProt
- P18850
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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