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ATF6 抗体 (C-Term)

Cited in 1 publication. This 兔 多克隆 anti-ATF6 antibody specifically detects ATF6 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2854487
发货至: 中国
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Quick Overview for ATF6 抗体 (C-Term) (ABIN2854487)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

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宿主

  • 96
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克隆类型

  • 86
  • 22
多克隆

标记

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This ATF6 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

KO Validated
  • 抗原表位

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    C-Term

    特异性

    This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form.,Knockdown/Knockout validation was supported by references (PMID:29535165)

    交叉反应

    人, 小鼠

    产品特性

    Rabbit polyclonal antibody to ATF6 (activating transcription factor 6)
    ATF6 antibody [C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF6. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Validatio: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wang, Lai, Yang, Lin, Chen, Tsai: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    activating transcription factor 6

    背景

    ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]

    Cellular Localization: Endoplasmic reticulum membrane , Processed cyclic AMP-dependent transcription factor ATF-6 alpha: Nucleus

    分子量

    75 kDa

    基因ID

    22926

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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