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SIAH1 抗体 (N-Term)

This anti-SIAH1 antibody is a 兔 多克隆 antibody detecting SIAH1 in IF 和 ICC. Suitable for 人.
产品编号 ABIN2854482
发货至: 中国

Quick Overview for SIAH1 抗体 (N-Term) (ABIN2854482)

抗原

See all SIAH1 抗体
SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

适用

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宿主

  • 51
  • 2
  • 2

克隆类型

  • 53
  • 2
多克隆

标记

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This SIAH1 antibody is un-conjugated

应用范围

  • 40
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Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 7
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    • 1
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    N-Term

    交叉反应

    小鼠

    产品特性

    Rabbit polyclonal antibody to SIAH1 (seven in absentia homolog 1 (Drosophila))
    SIAH1 antibody [N1], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SIAH1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

    别名

    siah E3 ubiquitin protein ligase 1

    背景

    This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

    Cellular Localization: Cytoplasm , Nucleus

    分子量

    31 kDa

    基因ID

    6477

    UniProt

    Q8IUQ4
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